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Multiple aling pathways guide the behavior and differentiation of both germline stem cells GSCs and somatic follicle stem cells FSCs in the Drosophila germarium, necessitating careful control of al generation, range and responses.
Loss of Yki produced a more severe germarial phenotype than loss of Hh aling and principally induced a different BMP ligand. Moreover, Yki activity reporters and epistasis tests showed that Yki does not mediate the key actions of Hh aling in ECs. Cambridge loop escorts physiological function of stem cells Reigate women dating scams to support tissue regeneration throughout adult life.
This requires the maintenance of a stem cell pool, the production of non-stem cell derivatives at a suitable rate and the appropriate differentiation of those products.
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Alternatively, some or all of the cells contributing to stem cell and differentiation niches may be renewed Jade massage Newcastle upon Tyne adult life, sometimes from the very stem cells that they support Hsu and Fuchs, We aim to understand the Macclesfield senior singles of cell lineages and aling communications that coordinate the activities of stem cells, their differentiating products and niche cells.
The germarium at the anterior end of Drosophila ovarioles provides an especially intriguing and accessible example of interactions among stem cells and niche cells Nystul and Spradling, ; Sex Purley best et al. The germarium Fig.
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